Article ID Journal Published Year Pages File Type
10816453 Cellular Signalling 2012 9 Pages PDF
Abstract
► In this review we analyze the state-of-art of Cdk5 signaling outside the nervous system. ► We described novel roles for Cdk5 in transcription, translation and cell cycle regulation. ► We report the pathological roles for Cdk5 in cancer, senescence, muscular dystrophy and diabetes. ► Alternative isoform functions are described. ► We envision novel roles for the Cdk5 kinase in territories outside the nervous system.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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