Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10816453 | Cellular Signalling | 2012 | 9 Pages |
Abstract
⺠In this review we analyze the state-of-art of Cdk5 signaling outside the nervous system. ⺠We described novel roles for Cdk5 in transcription, translation and cell cycle regulation. ⺠We report the pathological roles for Cdk5 in cancer, senescence, muscular dystrophy and diabetes. ⺠Alternative isoform functions are described. ⺠We envision novel roles for the Cdk5 kinase in territories outside the nervous system.
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Authors
Erick Contreras-Vallejos, Elias Utreras, Christian Gonzalez-Billault,