Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10816477 | Cellular Signalling | 2012 | 15 Pages |
Abstract
⺠HUVEC and EAhy926 endothelial cells were exposed to SIN-1, a peroxynitrite donor. ⺠SIN-1 induced Nrf2 activation, HO-1 overexpression and UPR activation in cells. ⺠Peroxynitrite protected cells against cell death induced by serum starvation. ⺠Peroxynitrite limited apoptosis, favoring LC3-II formation in a Nrf2 dependent way.
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Authors
Laurine Mattart, Damien Calay, Dorothy Simon, Laura Roebroeck, Ludmilla Caesens-Koenig, Martine Van Steenbrugge, Virginie Tevel, Carine Michiels, Thierry Arnould, Karim Zouaoui Boudjeltia, Martine Raes,