Article ID Journal Published Year Pages File Type
10816480 Cellular Signalling 2012 9 Pages PDF
Abstract
► LPLI promotes YAP cytoplasmic translocation in an Akt-dependent manner. ► LPLI protects cell from Aβ25-35-induced apoptosis through Akt activation. ► Activated Akt by LPLI promotes YAP phosphorylation on S127. ► Phosphorylated YAP separates from p73 and inhibits Bax expression. ► LPLI inhibits Aβ25-35-induced apoptosis through Akt/YAP/p73 pathway.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, , ,