Article ID Journal Published Year Pages File Type
10816486 Cellular Signalling 2012 7 Pages PDF
Abstract
► 5-HT1A receptors regulate phosphorylation of GSK3 in the hippocampus. ► PI3K/Akt signaling pathway mediates regulation of GSK3 by 5-HT1A receptors. ► 5-HT1A receptor-induced inhibition of contextual fear learning is GSK3β-dependent. ► Fluoxetine regulates phosphorylation of GSK3 in the hippocampus. ► Regulation of GSK3 is an intermediate of fluoxetine's anti-immobility effect.
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