| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10816488 | Cellular Signalling | 2012 | 10 Pages |
Abstract
⺠Silencing MMP-9 and uPAR/cathepsin B reduce SSAT expression in vitro and in vivo. ⺠Our treatments reduces the interaction of α9β1 and SSAT with uPAR or cathepsin B. ⺠SSAT knockdown inhibits the migration potential of glioma xenograft cells. ⺠Kir4.2 silencing inhibits uPAR, MMP-9 or cathepsin B-mediated glioma cell migration. ⺠MMP-9 and uPAR/cathepsin B silencing reduces the co-localization of α9 with Kir4.2.
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Authors
Krishna Kumar Veeravalli, Shivani Ponnala, Chandramu Chetty, Andrew J. Tsung, Meena Gujrati, Jasti S. Rao,