| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10816492 | Cellular Signalling | 2012 | 6 Pages |
Abstract
⺠Treatment of breast cancer cells with EGFR inhibitors leads to ErbB3 upregulation. ⺠ErbB3 is upregulated both at protein and mRNA levels. ⺠EGFR inhibitor treatment also leads to upregulation of ErbB2. ⺠This response might mediate resistance to EGFR-targeted cancer treatment.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Lene Melsæther Grøvdal, Jiyoung Kim, Mikkel Roland Holst, Stine Louise Jeppe Knudsen, Michael Vibo Grandal, Bo van Deurs,