| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10816543 | Cellular Signalling | 2005 | 6 Pages |
Abstract
Modulation of immune responses is an important strategy employed by pathogens to enable their survival in host organisms. Secreted immunomodulatory molecules are key weapons in the pathogen's battle with the host immune system. In this review, we will discuss the immunomodulatory effects of the phosphorylcholine-containing filarial nematode glycoprotein, ES-62, on the host immune system and summarise the results of our studies to identify the intracellular signalling pathways targeted by ES-62 to achieve these effects.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Helen S. Goodridge, Maureen R. Deehan, William Harnett, Margaret M. Harnett,