Article ID Journal Published Year Pages File Type
10816563 Cellular Signalling 2011 14 Pages PDF
Abstract
► Molecular chaperones are housekeeping factors of the cytoskeleton network. ► Cytoprotective roles involve apoptosis inhibition, regulation of organelle homeostasis and protein scaffolding. ► Unlike heat-shock proteins, changes in cytoskeletal filaments in response to stress are tissue-dependent. ► Hsp90 provides biological properties to proteins with a preserved tertiary structure. ► Some TPR-domain immunophilins show antagonistic action on the cytoskeletal organization.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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