| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10816996 | Cellular Signalling | 2008 | 9 Pages |
Abstract
In conclusion, our assay provides a unique and highly sensitive method to analyze PDE activity in living cells. It allows to sense cAMP gradients around particular PDE molecules and to study the pharmacological effects of selective inhibitors on localized cAMP signalling.
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Authors
Sabine Herget, Martin J. Lohse, Viacheslav O. Nikolaev,