Neonatal infections due to multi-resistant strains: Epidemiology, current treatment, emerging therapeutic approaches and prevention

Article ID	Journal	Published Year	Pages	File Type
10817282	Clinica Chimica Acta	2015	7 Pages	PDF

Abstract

The aim of the review is to highlight the current knowledge on antibiotic resistance in the neonatal population, the possible therapeutic choices, and the prevention strategies to adopt in order to reduce the emergency and spread of resistant strains.

Keywords

MDR IDSA VLBW ESBL VRE CoNS CA-MRSA HA-MRSA ECDC GBS Hospital-associated MRSA GNB XDR vancomycin-intermediate S. aureus ASP EMA CDC Klebsiella pneumoniae carbapenemase VRSA gPb CPE FDA Carbapenemase-producing Enterobacteriaceae Community-associated MRSA Late-onset sepsis Antibiotics European Medicines agency the Food and Drug Administration MRSA methicillin-resistant Staphylococcus aureus Coagulase-negative Staphylococcus Vancomycin-resistant enterococci Infectious Diseases Society of America Los Gram-positive bacteria Gram-negative bacteria NICU Extensively drug-resistant Antimicrobial treatment World Health Organization Early-onset sepsis Neonatal sepsis Extended spectrum β-lactamase EOs MALDI-TOF MS CSF Cerebrospinal fluid European Centre for Disease Prevention and Control PVL multi-drug resistant Multidrug-resistance Neonate very low birth weight infants neonatal intensive care unit polymerase chain reaction PCR VISA Panton-Valentine leukocidin WHO group B Streptococcus