Article ID Journal Published Year Pages File Type
10817302 Clinica Chimica Acta 2005 8 Pages PDF
Abstract
The proteomic study of 6-OHDA-induced lesions in the nigrostriatial pathway allowed us to identify two proteins, α-enolase and β-actin, showing increased levels in the 6-OHDA-lesioned brain tissues compared to control. Previous studies described the same proteins as oxidized and proteins in Alzheimer's disease (AD) brain. Our preliminary data could mirror those results pointing out a common mechanism of neurodegenerative diseases.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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