Sensitive non-isotopic assays for autoantibodies to IA-2 and to a combination of both IA-2 and GAD65

Article ID	Journal	Published Year	Pages	File Type
10817318	Clinica Chimica Acta	2005	10 Pages	PDF

Abstract

Sensitive and specific ELISAs for measurement of autoantibodies to IA-2 and to a combination of IA-2 and GAD65 have been developed. These assays are suitable for screening large numbers of samples in diabetes prediction and prevention trials.

Keywords

IA-2 RHA DASP IAA autoantibodies NIBSC Hbd autoantigens TMB GAD65 glutamic acid decarboxylase Rheumatoid arthritis Insulin autoantibodies enzyme linked immunosorbent assay Autoantibody Healthy blood donors tetramethylbenzidine ELISA Diabetes mellitus Coefficient of Variation SLE National Institute for Biological Standards and Control

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

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Sensitive non-isotopic assays for autoantibodies to IA-2 and to a combination of both IA-2 and GAD65

Authors

Shu Chen, Jinny Willis, Clare Maclean, Rossitza Ananieva-Jordanova, Marie-Andrée Amoroso, Helen Brooking, Michael Powell, Anne Collins, Stuart Bennett, Sarah Mitchell, Peter Burne, Jadwiga Furmaniak, Bernard Rees Smith,