| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10817552 | Clinical Biochemistry | 2016 | 6 Pages |
Abstract
Genome-wide DNA methylation varied according to glucose tolerance. Methylation within non-promoter regions accounted for the majority of differentially methylated peaks identified, thus highlighting the importance of DNA methylation within these non-promoter regions in the pathogenesis of type 2 diabetes. This study suggests that DNA methylation within intergenic regions is a mechanism regulating microRNAs, another increasingly important epigenetic factor, during type 2 diabetes.
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Authors
Carmen Pheiffer, Rajiv T. Erasmus, Andre P. Kengne, Tandi E. Matsha,