| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10817910 | Clinical Biochemistry | 2015 | 7 Pages |
Abstract
Accurate determination of MK activity was enabled by sensitive and reproducible detection of MVAP using UPLC-MS/MS. The novel method may improve molecular characterization of MVK mutations, provide robust genotype-phenotype correlations, and accelerate compound screening for drug candidates restoring variant MK activity.
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Authors
Lukas Reitzle, Barbara Maier, Silvia Stojanov, Daniel Teupser, Ania C. Muntau, Michael Vogeser, Søren W. Gersting,