Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10818092 | Clinical Biochemistry | 2005 | 8 Pages |
Abstract
This is perhaps the largest LC-MS-based study to demonstrate that HbSSG levels are markedly increased in diabetic subjects with microangiopathy. Since diabetic subjects also exhibited increased lipid peroxidation and decreased GSH levels, it appears that enhanced oxidative stress may account for the increased HbSSG concentrations and altered reduction-oxidation (redox) signaling.
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Authors
Rangasamy Sampathkumar, Muthuswamy Balasubramanyam, Sadasivannair Sudarslal, Mohan Rema, Viswanthan Mohan, Padmanabhan Balaram,