Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10818301 | Clinical Biochemistry | 2005 | 5 Pages |
Abstract
Genetic variation at the PON1 locus has a strong influence on PON1 activity as well as on carotid IMT. These data indicate that PON1 is indeed involved in the pathogenesis of atherosclerosis. Whether this also translates into a role for PON1 in the occurrence of CVD events needs to be confirmed by large prospective studies in the general population.
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Authors
Mark Roest, Angelique C.M. Jansen, Arjan Barendrecht, Frank R. Leus, John J.P. Kastelein, Hieronymus A.M. Voorbij,