Article ID Journal Published Year Pages File Type
10822525 Current Opinion in Structural Biology 2012 7 Pages PDF
Abstract
► The Bacteroidetes of the human gut utilize Sus-like systems for glycan uptake. ► SusD-like proteins have an α-helical fold and bind glycans on the cell surface. ► SusD-like proteins may be involved in passing oligosaccharides to a TonB-porin for transport into the periplasm. ► Hybrid two component systems (HTCS) that control Sus genes have two classes of sensor domains that recognize glycan signal molecules. ► Signal transduction across the membrane in HTCS likely differs from classical two-component systems.
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