Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10822525 | Current Opinion in Structural Biology | 2012 | 7 Pages |
Abstract
⺠The Bacteroidetes of the human gut utilize Sus-like systems for glycan uptake. ⺠SusD-like proteins have an α-helical fold and bind glycans on the cell surface. ⺠SusD-like proteins may be involved in passing oligosaccharides to a TonB-porin for transport into the periplasm. ⺠Hybrid two component systems (HTCS) that control Sus genes have two classes of sensor domains that recognize glycan signal molecules. ⺠Signal transduction across the membrane in HTCS likely differs from classical two-component systems.
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Authors
David N Bolam, Nicole M Koropatkin,