| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10822532 | Current Opinion in Structural Biology | 2012 | 14 Pages |
Abstract
⺠X-ray free electron lasers produce X-ray pulses with extremely brilliant peak intensity and ultrashort pulse duration. ⺠The concept of 'diffraction-before-destruction' has been verified on biological samples at the Linac Coherent Light Source. ⺠The continuous diffraction patterns from single biological particles allow solving the classical 'phase problem'. ⺠Serial femtosecond crystallography has been used to determine the 3D structure of micron-sized protein crystals at high resolution. ⺠Coherent X-ray diffraction imaging of single virus particles has been experimentally demonstrated.
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Authors
Ilme Schlichting, Jianwei Miao,