Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10822544 | Current Opinion in Structural Biology | 2013 | 11 Pages |
Abstract
⺠Wet molten globules (MGs) have decreased packing relative to the native state. ⺠Dry MGs have native-like structure but are expanded and have dry interiors. ⺠Extent and nature of packing in dry MGs remain to be elucidated. ⺠Packing defects in native proteins can have functional relevance. ⺠Packing can also be studied by mutagenesis, deep sequencing and surface display.
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Authors
Sanchari Bhattacharyya, Raghavan Varadarajan,