Article ID Journal Published Year Pages File Type
10822550 Current Opinion in Structural Biology 2013 9 Pages PDF
Abstract
► We review the recent advances made from the study of related proteins. ► We relate pathway malleability to the balance between foldons and helical propensity. ► We speculate why different topologies respond differently to mutation. ► We discuss the role of kinetic intermediates in folding pathways. ► We explain why it is important to study several members from each protein fold.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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