Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10822550 | Current Opinion in Structural Biology | 2013 | 9 Pages |
Abstract
⺠We review the recent advances made from the study of related proteins. ⺠We relate pathway malleability to the balance between foldons and helical propensity. ⺠We speculate why different topologies respond differently to mutation. ⺠We discuss the role of kinetic intermediates in folding pathways. ⺠We explain why it is important to study several members from each protein fold.
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Authors
Adrian A Nickson, Beth G Wensley, Jane Clarke,