Article ID Journal Published Year Pages File Type
10822554 Current Opinion in Structural Biology 2013 7 Pages PDF
Abstract
► TAL effectors are highly modular, easily programmable gene targeting proteins. ► Recent crystallographic analyses of TAL effectors have illustrated the basis for DNA recognition. ► Site-specific gene modification reagents using TAL effector scaffolds have recently been reported. ► The mechanism of target site search and acquisition by TAL effectors is an important question.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, , , ,