Article ID Journal Published Year Pages File Type
10822561 Current Opinion in Structural Biology 2013 7 Pages PDF
Abstract
► Single-molecule analyses revealed diffusive behaviors of DNA repair proteins. ► 1D and 3D search and intersegmental transfer are used to locate the target loci. ► MutS forms distinct clamps on DNA before and after mismatch recognition. ► RAD52 uses 1D sliding to impose quality control on annealing of complementary strands. ► Homology search by RecA is facilitated by intersegmental transfer and 1D sliding.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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