Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10822561 | Current Opinion in Structural Biology | 2013 | 7 Pages |
Abstract
⺠Single-molecule analyses revealed diffusive behaviors of DNA repair proteins. ⺠1D and 3D search and intersegmental transfer are used to locate the target loci. ⺠MutS forms distinct clamps on DNA before and after mismatch recognition. ⺠RAD52 uses 1D sliding to impose quality control on annealing of complementary strands. ⺠Homology search by RecA is facilitated by intersegmental transfer and 1D sliding.
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Authors
Maria Spies,