| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10822601 | Current Opinion in Structural Biology | 2013 | 6 Pages |
Abstract
- Large monomeric proteins suffer from spectral crowding.
- Nonuniform sampling of 3D and 4D data optimizes spectral resolution.
- Selective methyl labeling and tailored NMR experiments provide distance constraints.
- Large multimeric proteins are studied with divide and conquer approach.
- Multimeric proteins are studied by combining NMR methods with other techniques.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Dominique P Frueh, Andrew C Goodrich, Subrata H Mishra, Scott R Nichols,