Article ID Journal Published Year Pages File Type
10822772 Current Opinion in Structural Biology 2005 7 Pages PDF
Abstract
Self-splicing group I introns have served as a model for RNA catalysis and folding for over two decades. New three-dimensional structures now bring the details into view. Revelations include an unanticipated turn in the RNA backbone around the guanosine-binding pocket. Two metal ions in the active site coordinate the substrate and phosphates from all three helical domains.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
,