| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10823388 | DNA Repair | 2012 | 9 Pages |
Abstract
⺠We describe a comprehensive set of assays to study genomic DNA damage tolerance. ⺠Ubiquitinated PCNA (PCNA-Ub), Polη, Rev1, and Rev3 are important for UV tolerance. ⺠PCNA-Ub is involved in bypass of CPD and (6-4)PP lesions, early after UV exposure. ⺠Rev1 plays PCNA-Ub-dependent and -independent roles in bypass of (6-4)PP. ⺠Late bypass of CPD requires PCNA-Ub, but not Polη.
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Authors
Piya Temviriyanukul, Sandrine van Hees-Stuivenberg, Frédéric Delbos, Heinz Jacobs, Niels de Wind, Jacob G. Jansen,