Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10823396 | DNA Repair | 2013 | 8 Pages |
Abstract
⺠Arabidopsis MSH2 and MSH7 were expressed in Saccharomyces cerevisiae. ⺠AtMSH2 and AtMutSγ failed to complement the hypermutator phenotype of a msh2 deficient strain. ⺠AtMutSγ generated a 4-fold increase in CAN1 forward mutation rate on MMR proficient cells. ⺠AtMutSγ increased accumulation of base pair changes from G:C to A:T and T:A to C:G, G:C or A:T.
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Authors
Rodrigo Gómez, Claudia P. Spampinato,