Article ID Journal Published Year Pages File Type
10823414 DNA Repair 2013 7 Pages PDF
Abstract
► dCTPase-deficient mutants (dcd) of E. coli are mutators. ► dcd and nucleoside diphosphate kinase (ndk) mutants possess defined dNTP changes. ► In vivo dNTP changes correlate with the types of in vivo DNA replication errors. ► In vivo dNTP levels are kept low to facilitate proofreading of replication errors.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Mutational consequences of dNTP pool imbalances in E. coli
Authors
, ,