Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10823451 | DNA Repair | 2012 | 8 Pages |
Abstract
⺠Mutator mutants of E. coli are described with altered ribonucleotide reductase (RNR). ⺠RNR mutants display altered dNTP pools and corresponding mutational specificities. ⺠Mutants are found at the enzyme's allosteric activity and specificity sites. ⺠A novel regulatory important region is discovered in R2 subunit of RNR.
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Authors
Deepti Ahluwalia, Rachelle J. Bienstock, Roel M. Schaaper,