Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10823490 | DNA Repair | 2012 | 13 Pages |
Abstract
⺠Pol μ is a global player that increases the efficiency and the fidelity of NHEJ. ⺠Pol μ is implicated in the repair of substrates that do not undergo DNA synthesis. ⺠DNA synthesis activity of Pol μ is non-essential for NHEJ in a cellular context. ⺠Diverse repair events are produced according to the type of NHEJ impairment. ⺠Pol μ-dependent molecular landscapes of NHEJ events in primary cells.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Romain Chayot, Benjamin Montagne, Miria Ricchetti,