Article ID Journal Published Year Pages File Type
10823491 DNA Repair 2012 11 Pages PDF
Abstract
► Reversibility of senescence in yeast cells was tested using two approaches. ► Despite telomere damage, most cells were viable after telomerase reactivation. ► Mating of senescent cells with normal cells also restored growth capability. ► Rescue by telomerase differed in checkpoint mutants and recombination mutants. ► Cells rescued by telomerase exhibited shortened telomeres.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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