| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10823495 | DNA Repair | 2012 | 8 Pages |
Abstract
⺠To resolve DSBs DNA ends are brought together by protein complexes. ⺠Ku heterodimers recognize specifically DNA ends as shown by EM. ⺠Ku alone is not sufficient for DNA end bridging but requires Dnl4/Lif1 (Ligase IV/XRCC4). ⺠Ligase IV mediates end-bridging by bringing two Ku-bound DNA ends.
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Authors
Patricia Grob, Teri T. Zhang, Ryan Hannah, Hui Yang, Melissa L. Hefferin, Alan E. Tomkinson, Eva Nogales,