Article ID Journal Published Year Pages File Type
10823496 DNA Repair 2012 10 Pages PDF
Abstract
► MtSSB inhibits processing of damaged bases and AP-sites in ssDNA. ► UNG1 is recruited to mtSSB bound to ssDNA. ► DNA repair inhibition by mtSSB may protect against nicks at replication forks.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
mtSSB may sequester UNG1 at mitochondrial ssDNA and delay uracil processing until the dsDNA conformation is restored
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