Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10823519 | DNA Repair | 2011 | 13 Pages |
Abstract
⺠We characterized the first steps of global-genome repair in human cells. ⺠We examined the UVC-response of cells silenced for XPC and RAD23Aand/orB genes. ⺠RAD23A and RAD23B display distinct roles in DNA repair. ⺠XPC is essential for the localization of CENTRIN 2 to nuclear damaged areas. ⺠The CENTRIN 2 trapping may indirectly perturb proliferation and contribute to NER.
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Authors
Emilie Renaud, Laurent Miccoli, Natalie Zacal, Denis S. Biard, Constantin T. Craescu, Andrew J. Rainbow, Jaime F. Angulo,