Article ID Journal Published Year Pages File Type
10823519 DNA Repair 2011 13 Pages PDF
Abstract
► We characterized the first steps of global-genome repair in human cells. ► We examined the UVC-response of cells silenced for XPC and RAD23Aand/orB genes. ► RAD23A and RAD23B display distinct roles in DNA repair. ► XPC is essential for the localization of CENTRIN 2 to nuclear damaged areas. ► The CENTRIN 2 trapping may indirectly perturb proliferation and contribute to NER.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, , , , , , ,