Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10823647 | DNA Repair | 2005 | 12 Pages |
Abstract
By studying the chromatin structure of ribosomal genes in yeast, our knowledge of the fate of nucleosomes during transcription and DNA replication has improved considerably [R. Lucchini, J.M. Sogo, The dynamic structure of ribosomal RNA gene chromatin, in: M.R. Paule (Ed.), Transcription of Ribosomal RNA Genes by Eukaryotic RNA Polymerase I, Springer-Verlag/R.G. Landes Company, 1998, pp. 254-276]. How nuclear processes such as DNA repair take place in chromatin is still largely unknown, and in this review I discuss how the yeast rDNA locus may be exploited to investigate DNA repair and chromatin modification in vivo.
Keywords
XPCCSBXPGXPDCPDsXPBNTSSIRTCrTFIIHRDNAXPANoRCISWINERxeroderma pigmentosumRNA polymerase ISWI/SNFGGRChromatin remodelingsinChoChinese Hamster OvaryTranscription-coupled repairnucleotide excision repairGlobal genomic repairsilent information regulatorFACTCyclobutane pyrimidine dimersfacilitates chromatin transcriptionimitation switchCockayne syndromehistone deacetylaseshistone acetyltransferasesRibosomal genesHAT
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Authors
Antonio Conconi,