Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10825670 | Methods | 2014 | 10 Pages |
Abstract
- We describe computational methodologies for designing RNA nanocubes.
- 3 different cube designs are computationally and experimentally characterized.
- An Anisotropic Network Model is used to understand the dynamic nature of the cubes.
- Computational results explain and predict the experimental outcomes.
- Outcomes include cube sizes, melting temperatures and assembly yields.
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Authors
Kirill A. Afonin, Wojciech Kasprzak, Eckart Bindewald, Praneet S. Puppala, Alex R. Diehl, Kenneth T. Hall, Tae Jin Kim, Michael T. Zimmermann, Robert L. Jernigan, Luc Jaeger, Bruce A. Shapiro,