Gene expression analysis in biomarker research and early drug development using function tested reverse transcription quantitative real-time PCR assays

Article ID	Journal	Published Year	Pages	File Type
10825908	Methods	2013	10 Pages	PDF

Abstract

âº Function tested RT-qPCR assays used for biomarker research. âº High throughput application for relative quantification of gene expression levels. âº Biomarker discovery and verification for early clinical drug development.

Keywords

ALAS1 RT–qPCR Formalin-fixed paraffin-embedded tissue TGI hypoxanthine phosphoribosyltransferase-1 HPRT1 PHC Reverse transcription qPCR qPCR HER2 Biomarker High throughput Personalized health care gene expression profiling Tumor Growth Inhibition quantitative real-time PCR quantification cycle Human epidermal growth factor receptor 2

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

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Gene expression analysis in biomarker research and early drug development using function tested reverse transcription quantitative real-time PCR assays

Authors

Sabine Lohmann, Andrea Herold, Tobias Bergauer, Anton Belousov, Gisela Betzl, Mark Demario, Manuel Dietrich, Leopoldo Luistro, Manuela Poignée-Heger, Kathy Schostack, Mary Simcox, Heiko Walch, Xuefeng Yin, Hua Zhong, Martin Weisser,