| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10825921 | Methods | 2013 | 9 Pages |
Abstract
To evaluate the epigenetic effects on miRNA genes in CRC, we investigated the influence of DNA methylation on miR-34b, miR-34c and miR-9-1 expression. We aimed to verify the relationship between the methylation status of these miRNA genes and their relative expression in tumor samples. For the quantification of DNA methylation we adopted a method based on Differential High Resolution Melting (D-HRM).
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Authors
Serena Vinci, Stefania Gelmini, Irene Mancini, Francesca Malentacchi, Mario Pazzagli, Cristina Beltrami, Pamela Pinzani, Claudio Orlando,