| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10825924 | Methods | 2013 | 6 Pages |
Abstract
Using this system, we have profiled thousands of biofluid samples including blood derived plasma and serum. An extensive quality control (QC) system has been implemented in order to secure technical excellence and reveal any unwanted bias coming from pre-analytical or analytical variables. We present our approaches to sample and RNA QC as well as data QC and normalization. Specifically we have developed normal reference ranges for circulating miRNAs in serum and plasma as well as a hemolysis indicator based on microRNA expression.
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Authors
Thorarinn Blondal, Søren Jensby Nielsen, Adam Baker, Ditte Andreasen, Peter Mouritzen, Maria Wrang Teilum, Ina K. Dahlsveen,