| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10826126 | Methods | 2012 | 11 Pages |
Abstract
⺠Direct analysis of native drug-protein complexes with ESI-/MALDI-MS. ⺠Analysis of drug induced structural changes in target proteins. ⺠High through put MS based enzymatic assays for drug screening. ⺠Global analysis of cellular protein and PTM changes in response to drug treatment. ⺠Affinity/activity based drug target deconvolution and selectivity profiling.
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Authors
Nico Zinn, Carsten Hopf, Gerard Drewes, Marcus Bantscheff,