Article ID Journal Published Year Pages File Type
10826192 Methods 2012 8 Pages PDF
Abstract
► We present a new method for detection of DNA sequences with G-quadruplex forming potential, called ddiQFP. ► ddiQFP predicts G-quadruplexes formed from G-runs located on both strands of a DNA duplex. ► Yeast ddiQFP motifs distribute non-randomly, including in the nuclear vs. mitochondrial genomes. ► The G-quadruplex helicase Pif1 not only preferentially targets intramolecular QFP but also ddiQFP.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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