Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10826511 | Methods | 2007 | 6 Pages |
Abstract
The present study was carried out to examine the anti-inflammatory activity of the inner leaf gel component of Aloe barbadensis Miller. A simple in vitro assay was designed to determine the effect of the inner gel on bacterial-induced pro-inflammatory cytokine production, namely TNF-α and IL-1β, from peripheral blood leukocytes stimulated with Shigella flexneri or LPS. This report describes the suppression of both cytokines with a freeze-dried inner gel powder and a commercial health drink from the same source. Comparison was made with a human monocytic cell-line (THP-1 cells) and a similar trend in responses was demonstrated.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Fatema Habeeb, Graham Stables, Fiona Bradbury, Stephanie Nong, Pamela Cameron, Robin Plevin, Valerie A. Ferro,