| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10826574 | Methods | 2005 | 8 Pages |
Abstract
Multidimensional liquid chromatography techniques have been coupled to tandem mass spectrometry to provide a robust method to identify proteins in complex mixtures. Data acquisition is interfaced directly with search algorithms for identification through cross-correlation with databases. This review describes the most recent advances in methodologies for protein identification by mass spectrometry and describes the limitations of the application of the technologies.
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Authors
Claire Delahunty, John R. Yates III,