Article ID Journal Published Year Pages File Type
10826635 Methods 2005 14 Pages PDF
Abstract
This paper will give a complete methodological approach to the processing of oligonucleotide microarray data from postmortem tissue, particularly brain matter. Attention will be drawn to each of the important stages in the process; specifically the quality control, gene expression value calculation, multiple hypothesis testing and correlation analyses. We shall initially discuss the theoretical foundations of each individual method and subsequently apply the ensemble to a sample data set to illustrate and visualise important points.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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