Article ID Journal Published Year Pages File Type
10827082 Microvascular Research 2011 8 Pages PDF
Abstract
► HG impairs endothelium-dependent vasodilation in coronary arterioles. ► HG impairs EDHF-mediated arteriolar dilation via the elevation of superoxide. ► HG reduces endothelial cytochrome P450 (CYP) activity and EET production. ► HG reduces CYP activity by increasing superoxide production.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
High glucose impairs EDHF-mediated dilation of coronary arterioles via reduced cytochrome P450 activity
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