| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10827088 | Microvascular Research | 2011 | 6 Pages |
Abstract
⺠In patients with acute heart failure there is an important decline in the counter regulatory effects of endogenous vasodilators. ⺠Reduction of renal excretion of ADMA/SDMA is due to acute renal impairment function in patients with acute heart failure. ⺠Acute congestive heart failure leads to a under-expression of DDAH-1 enzyme determining a lack of ADMA metabolism with consequent increase in its plasma concentration.
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Authors
Lorenza Speranza, Sara Franceschelli, Nicolantonio D'Orazio, Raffaella Gaeta, Tonino Bucciarelli, Mario Felaco, Alfredo Grilli, Graziano Riccioni,