| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10827144 | Microvascular Research | 2012 | 8 Pages |
Abstract
⺠Exogenous Ang-2 stimulation of spheroids results in endothelial cell loss. ⺠Ang-2 antibody, MEDI3617, inhibits Ang-2 dependent endothelial cell loss. ⺠PMA stimulates endothelial cell loss of spheres in dose dependent manner. ⺠MEDI3617 able to decrease PMA induced endothelial cell loss even at a small dose. ⺠MEDI3617 reduces renal cell induced blood vessels in an in vivo intradermal assay.
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Authors
Nikolett Molnar, Dietmar W. Siemann,