| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10827165 | Microvascular Research | 2012 | 8 Pages |
Abstract
⺠Effects of hypoxia on brain microvascular endothelial cells (ECs) were examined. ⺠Hypoxia resulted in the increased expression and release of VEGF protein and mRNA. ⺠Increased ET-1 was released into the culture medium under hypoxic conditions. ⺠Hypoxia resulted in a decrease in expression of eNOS and suggests that hypoxia evokes a pro-angiogenic phenotype in ECs.
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Authors
J. Luo, J. Martinez, X. Yin, A. Sanchez, D. Tripathy, P. Grammas,