| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10833453 | Molecular Genetics and Metabolism | 2012 | 6 Pages |
Abstract
⺠Nitric oxide (NO) deficiency can contribute to mitochondrial diseases complications. ⺠NO deficiency in mitochondrial disorders can result from multiple factors. ⺠Arginine and citrulline supplementation can result in increased NO production. ⺠Arginine and citrulline can have therapeutic effects in mitochondrial diseases. ⺠Controlled clinical studies of the effects of arginine or citrulline are needed.
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Authors
Ayman W. El-Hattab, Lisa T. Emrick, William J. Craigen, Fernando Scaglia,