| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10833472 | Molecular Genetics and Metabolism | 2012 | 11 Pages |
Abstract
⺠Endogenous MMACHC and MMADHC detected in human cell lines. ⺠MMADHC did not bind cobalamin ⺠Identified MMADHC- and MMACHC- binding regions on MMACHC ⺠Disordered N-terminus of MMADHC is not involved in binding MMACHC ⺠Proposed function of MMADHC exerted through interaction with MMACHC
Keywords
DLS5′-deoxyadenosylcobalaminCN-PAGEMMACHCAdoCblMethylmalonyl-CoA mutaseCyanocobalamincblCMUTMeCblSECMBPAUCtris(2-carboxyethyl)phosphineanalytical ultracentrifugationTevSPRSurface plasmon resonanceProtein–protein interactioncircular dichroismTCEPmethylcobalaminMethionine synthaseHydroxocobalaminresonance unitvitamin B12Tobacco etch virusDynamic Light Scatteringmaltose binding proteincobalaminSize exclusion chromatographyCbl
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Authors
Justin C. Deme, Isabelle R. Miousse, Maria Plesa, Jaeseung C. Kim, Mark A. Hancock, Wayne Mah, David S. Rosenblatt, James W. Coulton,