Article ID Journal Published Year Pages File Type
10833533 Molecular Genetics and Metabolism 2012 6 Pages PDF
Abstract
► Peroxisome proliferator-activated receptors (PPARs), in particular, PPARα and γ, regulating lipid and carbohydrate metabolisms, and anti-oxidant and anti-inflammation systems in Wilson's disease (WD) were examined for the first time. ► PPARα and γ expressions were decreased and increased, respectively, according to the progression of liver damage of WD. ► PPARα and γ expressions were associated with steatosis and anti-oxidant system in WD.
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